Scavenger receptor class b type i翻译
WebThe scavenger receptor cysteine rich (SRCR) domain found in class A and class I SRs is part of a larger superfamily based on a ~100 amino acid domain that includes 6 (group A) to 8 (group B) cysteines forming an immunoglobulin-like fold held together by intramolecular disulfide bridges (Hohenester et al., 1999; Sarrias et al., 2004). Scavenger receptor class B, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, including enterocytes, the liver and adrenal gland. It is best known for its role in facilitating the uptake of cholesteryl esters from high-density lipoproteins in the liver. This process drives the … See more Scavenger receptor class B type 1 (SRB1) also known as SR-BI is a protein that in humans is encoded by the SCARB1 gene. SR-BI functions as a receptor for high-density lipoprotein. See more SR-BI has also been identified in the livers of non-mammalian species (turtle, goldfish, shark, chicken, frog, and skate), suggesting it emerged early in … See more Although malignant tumors are known to display extreme heterogeneity, overexpression of SR-B1 is a relatively consistent marker in cancerous tissues. While SR-B1 … See more SCARB1 along with CD81 is the receptor for the entry of the Hepatitis C virus into liver cells. See more Click on genes, proteins and metabolites below to link to respective articles. See more • Williams DL, Temel RE, Connelly MA (November 2000). "Roles of scavenger receptor BI and APO A-I in selective uptake of HDL cholesterol … See more
Scavenger receptor class b type i翻译
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WebApr 14, 2024 · Scavenger Receptor Class F Member 2 (SCARF2), also known as the Type F Scavenger Receptor Family gene, encodes for Scavenger Receptor Expressed by … WebMay 17, 2024 · The scavenger receptor class B type I (SR-BI), a member of the CD36 superfamily, is a membrane glycoprotein that functions as a HDL receptor [].SR-BI is well conserved between species and abundantly expressed in the liver and steroidogenic tissues where it mediates selective uptake of cholesteryl ester (CE) from HDL.
WebOct 1, 2002 · By reversible cross-linking with E2, we identified an 82 kDa glycosylated molecular species as the most likely candidate. Characterization of E2 binding after … WebJun 16, 2011 · Scavenger receptor class B type I (SR-BI) binds high-density lipoprotein (HDL) and mediates the selective uptake of cholesteryl esters (CE). Although the extracellular domain of SR-BI is critical for function, the structural characteristics of this region remain elusive. Using sulfhydryl labeling strategies, we report the novel finding that …
WebAbstract. Scavenger receptor class B, type I (SR-BI) is a crucial molecule in lipid metabolism, since the interaction of high-density lipoproteins (HDLs) with SR-BI is involved in reverse … WebJul 1, 2011 · Scavenger receptor class B type 1 (SR-B1) is a member of cluster of differentiation 36 (CD36) superfamily (1). The SR-B1 encoding SCARB1 gene is expressed in many tissues and cell types, including ...
WebOct 1, 2002 · By reversible cross-linking with E2, we identified an 82 kDa glycosylated molecular species as the most likely candidate. Characterization of E2 binding after chemical or enzymic modification of the cell surface led to the identification of the scavenger receptor type B class I (SR-BI) as the E2 receptor on HepG2 cells.
WebScavenger receptor class B type I (SR-BI), is a physiologically relevant HDL receptor that mediates selective uptake of lipoprotein (HDL)-derived cholesteryl ester (CE) in vitro and … elk bathroomWebJun 1, 2024 · Yuan B, Wu C, Wang X, et al. High scavenger receptor class B type I expression is related to tumor aggressiveness and poor prognosis in breast cancer. Tumour Biol. 2016; 37 :3581–3588. This clinical study shows that relatively high SR-BI expression in breast cancer tissue predicts a low survival and highlights the use of SR-BI as a biomarker for … elk basin outfitters crawford coloradoWebThe scavenger receptor class B type I (SR-BI) was the first molecularly well-defined cell-surface high-density lipoprotein (HDL) receptor to be described. B类I型清道夫受体是第一 … for charter bondsWebAlthough cellular uptake of vitamin E was initially described as a passive process, recent studies in the liver and brain have shown that SR-BI (scavenger receptor class B type I) is involved in this phenomenon. As SR-BI is expressed at high levels in the intestine, the present study addressed the involvement of SR-BI in vitamin E trafficking across … elk bathroom decorWebThe scavenger receptor class B type I(SR-BI) was the first molecularly well-defined cell-surface high-density lipoprotein(HDL) receptor to be described. B类I型清道夫受体是第一 … elk bath pictureWebScavenger receptor type B class I (SR-BI) is a multifunctional receptor capable of binding a wide array of native or modified lipoproteins, phospholipids, or bile acid micelles. In the hepatocyte, an important ligand for SR-BI is HDL, in which ApoA-I is the predominant apolipoprotein. Therefore, given the presence of ApoA-I in bile, SR-BI ... forchatgpt.cnWebSep 1, 2001 · The class A, type I and II scavenger receptors (SR-AI/II), the first SRs to be identified and cloned , are the subject of the article by Platt and Gordon in this Perspective series . Here, I will consider the class B, type I scavenger receptor, SR-BI, and studies that have refocused interest in scavenger receptors on lipoprotein metabolism. elk bath fire